The Medicines Company declares positive results from Inclisiran trial
Category: #health  By Nikita Chaurasia  Date: 2019-08-28
  • shareshare_icon
  • Twitter
  • Facebook
  • LinkedIn

The Medicines Company declares positive results from Inclisiran trial
  • The ORION-11 trial of inclisiran sodium 300 mg reached all secondary and primary endpoints with efficacy that is consistent with the findings from Phase 2 and 1 trials.
     
  • The trial evaluated that inclisiran was tolerated well and confirmed that its safety profile was as favorable as that shown in the ORION-3 and ORION-1 Phase 2 open-label extension studies.

The Medicines Company, a biopharmaceutical company dedicated to halt atherosclerosis progression and reduce cardiovascular risk, reportedly announced the positive topline outcomes of the first Phase 3 clinical trial examining the safety, tolerability and efficacy of inclisiran to reduce LDL-cholesterol by taking doses twice a year.

The ORION-11 trial of inclisiran sodium 300 mg reached all secondary and primary endpoints with efficacy that is consistent with findings from Phase 2 and 1 trials. The trial evaluated that inclisiran was tolerated well and confirmed that its safety profile was as favorable as that shown in the ORION-3 and ORION-1 Phase 2 open-label extension studies.

Detailed safety, tolerability and efficacy data from ORION-11 would be presented at a science session being conducted at the European Society of Cardiology’s ESC Congress 2019 in Paris on the 2nd of September at 8:30 am Central European Time (CET).

Mark Timney, CEO at The Medicines Company stated that it is an important occasion that strengthens the company’s confidence on in the immense potential of inclisiran to radically change cardiovascular disease treatment.

Mark added that he was proud of the company’s clinical development department’s commitment to quickly and efficiently develop this top-quality investigational therapy which could help millions of patients of ASCVD to attain treatment goals, have healthier lives and live longer.

This global study took place at 70 different sites across seven countries, ex-U.S. Each trial participant was given inclisiran sodium 300 mg, initially given as a subcutaneous injection, then again after three months and every six months after first three months.

 

Source Credit: https://www.themedicinescompany.com/investor/pr/3992694/

  • shareshare_icon
  • Twitter
  • Facebook
  • LinkedIn


About Author

Nikita Chaurasia     twitter

Nikita Chaurasia

Having always been daft at wordplay, Nikita Chaurasia, post the completion of post-graduation, commenced her journey into the content generation cosmos. Endowed with a professional MBA degree in Advertising and Public Relations, Nikita strives to integrate her creativ...

Read More..

More News By Nikita Chaurasia

Beijing’s quota clampdown could inhibit China’s crude oil import growth

Beijing’s quota clampdown could inhibit China’s crude oil import growth

By Nikita Chaurasia

According to a study conducted by Independent Commodity Intelligence Services (ICIS), China's growth in oil imports is expected to plummet to the lowest level in two decades during 2021, even with an estimated surge in refining rates during the l...

3D-model platform Sketchfab becomes Epic Games’ next big acquisition

3D-model platform Sketchfab becomes Epic Games’ next big acquisition

By Nikita Chaurasia

After RAD Game Tools and Quixel Megascans, American video game and software development company Epic Games Inc. has now acquired Sketchfab, the platform that boasts of over 4 million 3D models where artists can publish, modify, and sell their creatio...

Flipkart app now has a 3D camera for an immersive AR e-comm experience

Flipkart app now has a 3D camera for an immersive AR e-comm experience

By Nikita Chaurasia

Indian e-commerce giant Flipkart has introduced an Augmented Reality (AR) infused e-commerce experience with Flipkart Camera that would allow shoppers a real-life experience before purchasing a product. The novel feature built in the app should help ...