IMV announces updated data for Phase 2 DPX-Survivac trial in r/r DLBCL
Category: #health  By Mateen Dalal  Date: 2019-12-10
  • shareshare_icon
  • Twitter
  • Facebook
  • LinkedIn

IMV announces updated data for Phase 2 DPX-Survivac trial in r/r DLBCL
  • The updated results were presented in poster session at the ASH annual meeting
     
  • The study shows strong data for DPX-Survivac in combination with pembrolizumab

IMV Inc., a clinical-stage biopharmaceutical firm focusing on immunotherapy in oncology, recently announced updated results from SPiReL, which is an ongoing Phase 2 study of DPX-Survivac combined with pembrolizumab in patients suffering from refractory/ recurrent diffuse large B-cell lymphoma (r/r DLBCL). These updated results were presented through a poster session in Florida, at the 61st American Society of Hematology (ASH) Annual Meeting in Orlando.

Apparently, the poster consisted of an additional data arranged between the presentation and the submission of the abstract, as it continued to show a positive therapeutic profile as well as clinical benefit for r/r DLBCL patients associated with the treatment, who had received the combination regimen of DPX-Survivac.

Lead investigator of the clinical trial, Neil Berinstein, MD, FFCPC, ABIM and a hematologist at Toronto’s Sunnybrook Health Sciences Centre commented that the updated data exhibit favorable activity in patients who were treated with a combination regimen of DPX-Survivac for refractory/ recurrent diffuse large B-cell lymphoma.

Berinstein further added that as a contrast to both standard-of-care treatments as well as various other immunotherapeutic approaches for development, observation of the clinical advantage besides a safety profile shows the potential of DPX-Survivac to be able to reach out to a population of patients in a dire need of better options for treatment.

Chief Medical Officer at IMV, Joanne Schindler, M.D., D.V.M., stated that the results show a sturdy response in patients getting evaluated who followed the combination regimen consisting DPX-Survivac. It has continued to show a positive therapeutic profile especially for patients who were suffering from hard-to-treat cancers.

Schindler continued that the data validates the novel mechanism of DPX-Survivac that extends the earlier documented results for solid cancers to now surviving-expressing hematologic diseases. The company believes that it represents a meaningful alternative to chemotherapy regimens that are more toxic. The company is looking forward to obtaining topline results from the study as it prepares to introduce IMV-sponsored study in 2020 for r/r DLBCL.

 

Source Credit- https://ir.imv-inc.com/news-releases/news-release-details/updated-clinical-data-phase-2-spirel-study-evaluating-dpx

  • shareshare_icon
  • Twitter
  • Facebook
  • LinkedIn


About Author

Mateen Dalal     twitter

Mateen Dalal

A qualified electronics and telecommunication engineer, Mateen Dalal embarked on his professional journey working as a quality and test engineer. Harnessing his passion for content creation however, Mateen pens down industry-rich articles for ReportsGO.com and a few o...

Read More..

More News By Mateen Dalal

Xiaomi and Oppo team up with UNISOC to manufacture in-house 5G chipsets

Xiaomi and Oppo team up with UNISOC to manufacture in-house 5G chipsets

By Mateen Dalal

The two companies intend to introduce their custom-made sub-6GHz 5G chipsets by the end of 2021. UNISOC has managed to raise around USD 817.20 million for its new venture. Chinese electronics giants including Xiaomi Corp. and Guangdong Oppo Mob...

Twitter explored USD 4 billion takeover of audio-chat app Clubhouse

Twitter explored USD 4 billion takeover of audio-chat app Clubhouse

By Mateen Dalal

Twitter, an American microblogging service company, had touted plans of acquiring Clubhouse, an audio chat iPhone app and live drop-in audio networking platform. The deal was estimated to be valued at around USD 4 billion, as per reliable sources. T...

Beyond Meat sets up factory in China to expedite localized innovation

Beyond Meat sets up factory in China to expedite localized innovation

By Mateen Dalal

American plant-based meat substitute producer Beyond Meat has opened a new production facility in China. Apparently, this recent setup is the company’s first facility outside the U.S., making it the only multinational organization solely focusi...